Natriuretic Peptide Receptors, NPR-A and NPR-B, in Cultured Rabbit Retinal Pigment Epithelium Cells
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منابع مشابه
NPR-B natriuretic peptide receptors in human corneal epithelium: mRNA, immunohistochemistochemical, protein, and biochemical pharmacology studies
PURPOSE To demonstrate the presence of natriuretic peptide receptors (NPRs) in primary human corneal epithelial cells (p-CEPI), SV40-immortalized CEPI cells (CEPI-17-CL4) and in human corneal epithelium, and to define the pharmacology of natriuretic peptide (NP)-induced cGMP accumulation. METHODS NPR presence was shown by RT-PCR, western blot analysis, and indirect immunofluoresence. cGMP acc...
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Natriuretic peptide receptor A (NPR-A/GC-A) and B (NPR-B/GC-B) are members of the transmembrane guanylyl cyclase family that mediate the effects of natriuretic peptides via the second messenger, cGMP. Despite numerous reports of these receptors being down-regulated in response to various pathological conditions, no studies have actually measured desensitization and receptor internalization in t...
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This tutorial surveys the state-of-the-art techniques for interactive non-photorealistic rendering with an emphasis on applications to volume visualization. This first section begins by giving a general motivation behind the need for interactivity in NPR and discusses some of the general approaches toward achieving high-speed rendering. The second section surveys methods that have been develope...
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Several studies show that C-type natriuretic peptide (CNP) has a modulatory role in the digestive system. CNP administration reduces both jejunal fluid and bile secretion in the rat. In the present study we evaluated the effect of CNP on amylase release in isolated pancreatic acini as well as the receptors and intracellular pathways involved. Results showed that all natriuretic peptide receptor...
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Retinal pigment epithelium (RPE)-choroid-sclera preparations from black, dutch-belted rabbits were sealed in an Ussing chamber. The RPE-generated trans-RPE voltage (Ve) and electrical resistance (R) were monitored. Epinephrine (an alpha and beta adrenergic agonist) reduced Ve by as much as 39% without affecting R. A response to epinephrine was noted at concentrations as low as 1.4 X 10(-7) M. P...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1999
ISSN: 0021-5198
DOI: 10.1254/jjp.79.359